For Pharmaceutical Companies

The post discharge evidence window has been invisible. Until now.

Lumaris gives pharmaceutical market access, HEOR, and medical affairs teams access to High Fidelity Patient Evidence, structured, prospective, patient sourced data collected during the 90 day post discharge window where adherence failure happens, readmission risk peaks, and every existing real world data platform loses the signal.

HFPE vs. Traditional Claims Based Real World Evidence
Trisana Standard
Evidence Characteristic Claims / EHR Trisana HFPE
Data sourceAdministrative billingDirect patient engagement
Adherence timingDays or weeks afterWithin 72 hours
SDOH dataInferred from censusDirect patient reported
Behavioral signalsNot availableSelf efficacy, barriers
Day 90 coverage~12% retentionStructured through Day 90
Intervention layerObservation onlyEmbedded case management
Evidence Standard

High Fidelity Patient Evidence, a different category of data.

TriunityCX defines High Fidelity Patient Evidence as prospective, patient sourced behavioral and social data collected through direct structured engagement at defined protocol intervals across the 90 day post discharge window. HFPE is not derived from administrative transactions or inferred from population level proxies. It is collected directly from the patient through a structured case management protocol that captures what the patient is actually doing, not what was billed on their behalf.

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Medication Adherence
72 hour first fill status, MAV score, refill trajectory, fill delay reasons, and supply status captured at each protocol interval
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SDOH Barriers
Transportation, medication cost, housing stability, caregiver burden, and food security, direct patient reported, not inferred from zip codes
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Self Efficacy
Patient confidence score, health literacy level, and motivation trajectory across the full 90 day post discharge window
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Follow Up Status
Seven day appointment confirmation, specialist access, and emergency department visit detection at each touchpoint
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Clinical Profile
Primary discharge diagnosis across heart failure, COPD, pneumonia, and diabetes, the conditions with the highest readmission burden nationally, along with GDMT drug class, days since discharge, and relevant comorbidity context providing the clinical baseline for all behavioral signals

Existing platforms capture what was billed and what was dispensed, typically days or weeks after the clinical event occurred. Trisana captures what the patient is actually doing, within 72 hours of discharge, through direct structured engagement. That difference in data source produces a materially different category of evidence that is more behaviorally specific, more temporally precise, and more actionable for pharmaceutical market access and payer strategy than anything retrospective claims aggregation can produce.


Novel KPIs

Evidence outputs unavailable from any other real world data platform.

Lumaris surfaces a suite of novel key performance indicators derived from the HFPE evidence standard that pharmaceutical market access and HEOR teams cannot access through claims data, EHR aggregations, or any existing real world data vendor.

Adherence
Medication Adherence Velocity
The rate at which medication adherence is strengthening or declining across the post discharge window, providing a dynamic trajectory rather than a static fill event. This metric captures directional momentum that a single prescription fill record cannot produce regardless of how frequently claims data is refreshed.
Sample Cliff
Day 90 Engagement Retention
Patient engagement retention through Day 90 compared to the industry baseline data availability rate, quantifying the 76 days of evidence that Lumaris captures in the post discharge window that every existing real world data platform loses after Day 14. This is the metric that defines the Sample Cliff and the evidence gap Trisana closes.
Additional Novel KPIs

Lumaris surfaces six additional proprietary KPIs across behavioral, clinical, predictive, and data quality signal categories. The full KPI architecture is available to Lumaris partners upon execution of a data partnership agreement. Contact us to discuss what the complete evidence framework looks like for your therapeutic area.

The Sample Cliff

Every other platform loses the patient at Day 14. Lumaris does not.

Structured data collection in existing real world platforms drops sharply after the first two weeks following discharge. Claims data thins out, EHR entries stop, and prescription fill records capture only a billing transaction with no behavioral context attached. This gap occurs precisely during the window when most adherence failures originate and most readmissions are set in motion.

Trisana closes the post discharge evidence gap.

The gap between the two lines below represents 76 days of behavioral and social evidence that pharmaceutical companies cannot access through any existing real world data vendor, regardless of how large their patient database is.

Trisana Proprietary
Discharge Day 14 Day 30 Day 60 Day 90
Trisana protocol engagement
Industry baseline data availability
Unique Evidence Window
76 days
Days 14 through 90 post discharge, unavailable from any existing real world data vendor
Industry Day 90 Retention
~12%
Of patients have structured data collected by Day 90 in existing platforms
Trisana Evidence Standard
HFPE
Prospective, patient sourced, collected at structured protocol intervals
Commercial Applications

What pharmaceutical companies do with High Fidelity Patient Evidence.

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Market Access
Market access teams use HFPE to build payer arguments that go beyond claims derived outcomes data. Direct patient reported adherence evidence, SDOH context, and real world behavioral signals provide the patient centered evidence that payers and formulary committees increasingly require to justify premium pricing and favorable formulary positioning.
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Health Economics and Outcomes Research
HEOR teams use HFPE to understand the behavioral and social factors driving adherence failure in their patient populations, informing outcomes based contract design with payers and providing the real world context that strengthens post market surveillance submissions.
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Medical Affairs
Medical affairs teams use HFPE to understand how patients experience their drug in the real world beyond the clinical trial environment, including which patient subgroups respond differently and which social circumstances are most predictive of treatment discontinuation.
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Research and Development
Research and development teams use HFPE to design future clinical trials with realistic assumptions about post discharge patient behavior, improving the relevance of trial design to the real world conditions in which the drug will ultimately be used.

Partnership Tiers

Two ways to partner with Trisana through Lumaris.

Partnership pricing for both tiers is structured based on network scale, therapeutic area scope, and evidence maturity at the time of agreement. Contact us to discuss what a Lumaris partnership looks like for your organization.

Tier 1

Therapeutic Area Partnership

A pharmaceutical company with drugs in a relevant therapeutic area subscribes for access to aggregate cohort level evidence across the Trisana hospital network for their disease category. This tier is structured for organizations that want population level intelligence on patient behavior in their therapeutic area, with founding partner pricing available to early participants that is locked for the life of the agreement.

Tier 2

Drug Specific Evidence Partnership

A pharmaceutical company enters a more specific data use agreement scoped to patients discharged on their particular therapeutic agent, receiving evidence directly tied to their drug's real world performance in the post discharge window. This tier is structured for organizations that need drug specific adherence evidence, SDOH-outcomes correlation for a defined patient subgroup, and regulatory grade evidence outputs.

Full therapeutic area cohort analytics across the Trisana network
All novel KPIs including MAV, HFPE signals, SDOH correlation, and Sample Cliff retention
Cohort summary reports and HFPE methodology documentation
Access to the Lumaris evidence intelligence platform with embedded analytics
Evidence maturity milestone updates as the network scales toward publishable findings
Founding partner pricing locked for the life of the agreement
Everything in Tier 1, scoped to your specific therapeutic agent
Patient level adherence evidence on patients taking your drug post discharge
SDOH-outcomes correlation specific to your patient subgroup
Support for outcomes based contract design with payers
Regulatory submission grade evidence packages at network maturity
Priority access to publishable evidence outputs at 500 completed patient journeys
Evidence Outputs

Available downloads and reports.

Cohort Summary Report
Aggregate adherence analytics, SDOH distribution, and KPI summary for your therapeutic area
Available
HFPE Data Methodology Document
Signal architecture, collection protocol, de identification methodology, and data governance framework
Available
Predictive Signal Validation Report
Validated risk model outputs identifying early post discharge signals most predictive of adherence failure, activates at 200 completed patient journeys
200 patients required
Publishable Evidence Package
Peer review ready manuscript draft, statistical analysis, and regulatory submission grade evidence outputs
500 patients required
Evidence Maturity Progression
Active
Pilot Insights
Signal architecture, adherence patterns, SDOH barrier distribution across the active cohort
0 to 50 patients
Pending
Statistical Evidence
Predictive model training, risk score validation, and statistically credible cohort analysis
50 to 200 patients
Locked
Publishable Findings
Peer reviewed evidence outputs and regulatory submission grade data packages
200 to 500 patients
Get Started

TriunityCX is actively signing founding pharmaceutical partners nationally.

Founding partners access the Lumaris evidence framework at the lowest price point in the program's history, with pricing locked for the life of the agreement. As the hospital network scales and patient data volume grows, the value of the evidence partnership grows with it. Early partners shape the evidence framework in ways that later partners cannot.